Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 3/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10268152 | 0.83 | NR4A1 (0.50) | TUBB1ALDH1A1MAPTLMNANCF1 | |
| SCHEMBL16856647 | 0.82 | TUBB1 (0.37) | TUBB1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL18812296 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAHSD17B10ERN1 | |
| SCHEMBL12238327 | 0.81 | ALDH1A1 (0.38) | TUBB1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL2024267 | 0.78 | MAOB (0.45) | ALDH1A1 | |
| SCHEMBL12238283 | 0.78 | PTGDR2 (0.51) | ALDH1A1MAPTLMNAHSD17B10HPGD | |
| SCHEMBL29953054 | 0.77 | MAOB (0.56) | MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2331112 | 0.77 | PTGDR2 (0.50) | ALDH1A1MAPTLMNAHSD17B10HPGD | |
| SCHEMBL12264236 | 0.76 | PDE3B (0.48) | ALDH1A1CASP1CASP7HSD17B10 | |
| Lithium Ion SCHEMBL2331107 | 0.76 | PTGDR2 (0.36) | TUBB1ALDH1A1TRIM24TYRTRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048582-A1 | BIOSYNTHETICALLY GENERATED PYRROLINE-CARBOXY-LYSINE AND SITE SPECIFIC PROTEIN MODIFICATIONS VIA CHEMICAL DERIVATIZATION OF PYRROLINE-CARBOXY-LYSINE AND PYRROLYSINE RESIDUES | IRM LLC (BM) | 2010-04-29 | — | — | WO | disclosed |