SCHEMBL163652

SCHEMBL163652

[O]c1ccccc1C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.68
ALOX15 P16050 1/20 0.68
POLB P06746 1/20 0.58
CA12 O43570 3/20 0.56
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA4 P22748 3/20 0.56
CA7 P43166 3/20 0.56
CA9 Q16790 3/20 0.56
NAPRT Q6XQN6 3/20 0.56
KDM4E B2RXH2 1/20 0.56
HMGB1 P09429 1/20 0.56
HPGD P15428 1/20 0.56
CA6 P23280 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CA14 Q9ULX7 1/20 0.56
MAPT P10636 2/20 0.54
HDAC8 Q9BY41 1/20 0.54
AKR1C3 P42330 1/20 0.52
NR4A1 P22736 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL29674820 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15POLBCA12CA1
Phthalic Acid SCHEMBL8671920 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15POLBCA12CA1
Phthalic Acid SCHEMBL5668586 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15POLBCA12CA1
Phthalic Acid SCHEMBL10477086 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15POLBCA12CA1
Phthalic Acid SCHEMBL1808 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15POLBCA12CA1
Phthalic Acid SCHEMBL1686043 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15POLBCA12CA1
Phthalic Acid SCHEMBL146125 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15POLBCA12CA1
Phthalic Acid SCHEMBL1332278 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15POLBCA12CA1
Phthalic Acid SCHEMBL4452470 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15POLBCA12CA1
Phthalic Acid SCHEMBL29364035 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15POLBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1058 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109414401-B Biodegradable polymeric microsphere compositions for parenteral administration 阿代尔制药股份有限公司 2023-06-13 CN claimed
US-20230125630-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF UNIV MARYLAND (US) 2023-04-27 US claimed
US-11472927-B2 Polyphosphazenes, methods of making, and uses thereof UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2022-10-18 US claimed
CN-112266461-B Buffer material capable of being used in low-temperature environment and preparation method and application thereof 广东互典缓冲材料技术有限公司 2022-04-12 CN claimed
CN-112251183-B Pressure-sensitive hot melt adhesive capable of being used at low temperature and preparation method thereof 广东互典缓冲材料技术有限公司 2022-04-12 CN claimed
CN-109053463-B Method for converting diaryl ether into N-cyclohexyl aniline compound 兰州大学 2021-04-20 CN claimed
CN-112266461-A Buffer material capable of being used in low-temperature environment and preparation method and application thereof 广东互典缓冲材料技术有限公司 2021-01-26 CN claimed
CN-112251183-A Pressure-sensitive hot melt adhesive capable of being used at low temperature and preparation method thereof 广东互典缓冲材料技术有限公司 2021-01-22 CN claimed
CN-111936161-A IPSC-based vaccines as a prophylactic and therapeutic treatment of cancer 克洛里斯生物科学有限公司 2020-11-13 CN claimed
CN-109030589-B Tetra-beta-carboxyphenoxy metal phthalocyanine/graphene composite material and method 黑龙江工程学院 2020-10-02 CN claimed
US-5352673-A Administering to inactivate or inhibit phospholipase A REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE A CORP. OF CALIFORNIA 1994-10-04 US claimed
WO-1992022289-A1 NOVEL PHOSPHOLIPASE A2 INHIBITORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-12-23 WO claimed
US-5075491-A Ultraviolet radiation absorbers EASTMAN KODAK COMPANY (US) 1991-12-24 US claimed
EP-0301401-B1 LEUKOTRIENE ANTAGONISTS, PROCESS FOR THEIR PREPARATION, THEIR USE IN THE TREATMENT OF ILLNESSES HOECHST AKTIENGESELLSCHAFT (DE) 1991-11-27 EP claimed
US-5068348-A For food packaging EASTMAN KODAK COMPANY (US) 1991-11-26 US claimed
US-4851440-A ASTHMA HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-25 US claimed
EP-0301401-A2 Leukotriene antagonists, process for their preparation, their use in the treatment of illnesses HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-01 EP claimed
EP-0004026-B1 HYDROLYTICALLY STABLE ORTHO-ALKYLATED PHENYL PHOSPHONITES AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1982-05-05 EP claimed
US-4233207-A STABILIZING POLYMERS AGAINST OXIDATION, HEAT, AND RADIATION CIBA-GEIGY CORPORATION (US) 1980-11-11 US claimed
US-4138558-A Anthraquinone compounds NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1979-02-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230125630-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF PHOSPHO1, PLCG2, PLCG1 ALDH1A1 4658/4885ALOX15 1056/4885POLB 702/4885
US-11472927-B2 Polyphosphazenes, methods of making, and uses thereof PHOSPHO1, PLCG2, PLCG1 ALDH1A1 4658/4885ALOX15 1056/4885POLB 702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.