⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28999970 | 0.91 | MEN1 (0.31) | — | |
| SCHEMBL27737276 | 0.83 | MEN1 (0.30) | — | |
| SCHEMBL12530085 | 0.82 | LMNA (0.30) | — | |
| SCHEMBL12530599 | 0.82 | LMNA (0.30) | — | |
| SCHEMBL1750027 | 0.82 | LMNA (0.30) | — | |
| SCHEMBL14957876 | 0.81 | MAPT (0.33) | — | |
| SCHEMBL2169113 | 0.81 | MAPT (0.33) | — | |
| SCHEMBL1231115 | 0.81 | MAPT (0.33) | — | |
| SCHEMBL12530558 | 0.81 | MAPT (0.33) | — | |
| SCHEMBL31544405 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932277-B2 | Peptide inhibitors of hepatitis C virus replication | INTERMUNE, INC. (US) | 2011-04-26 | — | — | US | disclosed |
| US-20090297476-A1 | NOVEL PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-12-03 | — | — | US | disclosed |