SCHEMBL16366135

SCHEMBL16366135

CC1(C)c2ccccc2-c2ccc(N(c3ccc(-c4ccc5ccccc5c4)cc3)c3ccc4c(c3)C(C)(C)c3cc(-c5ccc(-c6ccccc6)cc5)ccc3-4)cc21

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 10/20 0.40
LPL P06858 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
ESR1 P03372 3/20 0.36
ESR2 Q92731 3/20 0.36
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
CYP1A1 P04798 1/20 0.34
CYP1B1 Q16678 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
AKT1 P31749 1/20 0.33
ACMSD Q8TDX5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10034350 1.00 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL10034420 1.00 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL16366430 1.00 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL10034348 1.00 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL17153730 1.00 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL17153662 1.00 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL23950945 1.00 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL10034406 1.00 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL16366541 1.00 PDK2 (0.40) PDK2LPLLIPGESR1ESR2
SCHEMBL21968964 0.99 PDK2 (0.39) PDK2LPLLIPGESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210002-A1 COMPOSITION, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20230210002-A1 COMPOSITION, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-11575087-B1 Organic electroluminescence device, light emitting device, organic electroluminescence display device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-02-07 US disclosed
US-20210328156-A1 MIXTURE, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-21 US disclosed
US-9871203-B2 Aromatic amine derivative, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-01-16 US disclosed
US-9871203-B2 Aromatic amine derivative, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-01-16 US disclosed
US-20150287921-A1 AROMATIC AMINE DERIVATIVE, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2015-10-08 US disclosed
US-20150287921-A1 AROMATIC AMINE DERIVATIVE, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2015-10-08 US disclosed
EP-2816025-A1 AROMATIC AMINE DERIVATIVE, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE Idemitsu Kosan Co., Ltd (JP) 2014-12-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150287921-A1 AROMATIC AMINE DERIVATIVE, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE RER1, AFF1, ESR2 PDK2 3794/4885LPL 3058/4885LIPG 1361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.