Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1636796 | 1.00 | P2RX7 (0.45) | P2RX7SCN9A | |
| SCHEMBL1637705 | 0.89 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL1637645 | 0.87 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL1636775 | 0.83 | P2RX7 (0.49) | P2RX7 | |
| SCHEMBL2841345 | 0.83 | P2RX7 (0.49) | P2RX7 | |
| SCHEMBL1636701 | 0.82 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL1637472 | 0.81 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL1636761 | 0.81 | P2RX7 (0.51) | P2RX7 | |
| SCHEMBL1635930 | 0.77 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL1636103 | 0.76 | P2RX7 (0.53) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932282-B2 | Imidazolidine carboxamide derivatives as P2X7 modulators | GLAXO GROUP LIMITED (GB) | 2011-04-26 | — | — | US | disclosed |
| CN-101679291-A | Imidazolidine carboxamide derivatives as P2X7 modulators | GLAXO GROUP LTD | 2010-03-24 | — | — | CN | disclosed |