Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336267 | 0.79 | CA1 (0.30) | — | |
| SCHEMBL12745355 | 0.77 | — | — | |
| SCHEMBL12784637 | 0.77 | — | — | |
| SCHEMBL16369411 | 0.77 | PDE3B (0.33) | PDE3BPDE3AHTR2CHTR2AHTR2B | |
| SCHEMBL16369410 | 0.77 | EIF4A3 (0.32) | — | |
| SCHEMBL2959355 | 0.75 | — | — | |
| SCHEMBL23625165 | 0.74 | NOTUM (0.40) | PDE3BPDE3ANOTUM | |
| SCHEMBL19130837 | 0.73 | LMNA (0.40) | HTR2CHTR2B | |
| SCHEMBL24165388 | 0.72 | NOTUM (0.39) | PDE3BPDE3AHTR2CNOTUM | |
| SCHEMBL2973303 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921361-B2 | Triazine, pyrimidine and pyridine analogs and their use as therapeutic agents and diagnostic probes | UNIVERSITY OF BASEL (CH) | 2014-12-30 | — | — | US | disclosed |