Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 5/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16368731 | 0.89 | BDKRB1 (0.49) | BDKRB1PTGER4PTGER2CNR1MAPK14 | |
| SCHEMBL765546 | 0.89 | BDKRB1 (0.53) | BDKRB1PTGER4PTGER2CNR1MAPK14 | |
| SCHEMBL16369343 | 0.87 | BDKRB1 (0.49) | BDKRB1PTGER4PTGER2CNR1MAPK14 | |
| SCHEMBL765146 | 0.87 | BDKRB1 (0.50) | BDKRB1PTGER4PTGER2CNR1MAPK14 | |
| SCHEMBL12239063 | 0.86 | BDKRB1 (0.60) | BDKRB1CNR1MAPK14F10CYP3A4 | |
| SCHEMBL12239081 | 0.86 | BDKRB1 (0.52) | BDKRB1PTGER4PTGER2CNR1MAPK14 | |
| SCHEMBL10121331 | 0.82 | BDKRB1 (0.60) | BDKRB1CNR1MAPK14CYP3A4MMP13 | |
| SCHEMBL10121385 | 0.81 | BDKRB1 (0.53) | BDKRB1PTGER4PTGER2CNR1MAPK14 | |
| SCHEMBL12239059 | 0.81 | BDKRB1 (0.53) | BDKRB1PTGER4PTGER2CNR1MAPK14 | |
| SCHEMBL12262806 | 0.81 | BDKRB1 (0.55) | BDKRB1PTGER4PTGER2CNR1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916589-B2 | Bradykinin B1-antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-23 | — | — | US | disclosed |