⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4361606 | 0.76 | — | — | |
| SCHEMBL11463109 | 0.74 | KDM4E (0.53) | — | |
| SCHEMBL20583714 | 0.73 | — | — | |
| SCHEMBL849958 | 0.72 | KDM4E (0.43) | — | |
| SCHEMBL11173191 | 0.72 | KDM4E (0.61) | — | |
| SCHEMBL11546051 | 0.72 | KDM4E (0.50) | — | |
| SCHEMBL4859549 | 0.72 | KDM4E (0.43) | — | |
| SCHEMBL31277728 | 0.71 | KDM4E (0.42) | — | |
| SCHEMBL23500956 | 0.70 | KDM4E (0.41) | — | |
| SCHEMBL24610541 | 0.70 | DHODH (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118151489-B | Photosensitive resin composition, photosensitive dry film and application thereof | 湖南初源新材料股份有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-118151490-B | Photosensitive resin composition, photosensitive dry film and application thereof | 湖南初源新材料股份有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-118151489-A | Photosensitive resin composition, photosensitive dry film and application thereof | 湖南初源新材料股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118151490-A | Photosensitive resin composition, photosensitive dry film and application thereof | 湖南初源新材料股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| EP-3215505-B1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | Bayer Pharma AG (DE) | 2019-07-24 | — | — | EP | disclosed |
| US-10118930-B2 | Piperidinylpyrazolopyrimidinones and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-11-06 | — | — | US | disclosed |
| US-20170334917-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | US | disclosed |
| EP-3215505-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | Bayer Pharma Aktiengesellschaft (DE) | 2017-09-13 | — | — | EP | disclosed |
| WO-2016071216-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-05-12 | — | — | WO | disclosed |
| EP-2611802-B1 | BICYCLIC AZA-HETEROCYCLES AND THEIR USE | BAYER IP GMBH (DE) | 2016-02-24 | — | — | EP | disclosed |
| US-5169850-A | Neurotropic or hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| US-5059691-A | Anxiolytic agents; hypotensive agents; nervous system disorders; cognition activators | AMERICAN CYANAMID COMPANY (US) | 1991-10-22 | — | — | US | disclosed |
| EP-0443312-A2 | 2,4,8-trisubstituted-3H-6H-1,4,5a,8a-tetraazaacenaphthylene-3,5-(4H)-diones | AMERICAN CYANAMID COMPANY (US) | 1991-08-28 | — | — | EP | disclosed |
| US-5013737-A | Hypotensive, anxiolytic, cognitive disorders | AMERICAN CYANAMID COMPANY (US) | 1991-05-07 | — | — | US | disclosed |
| US-4847256-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0264773-A1 | 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1988-04-27 | — | — | EP | disclosed |
| EP-0025819-B1 | SUBSTITUTED PYRAZOLO (1,5-A) PYRIMIDINES, AND THEIR PREPARATION | AMERICAN CYANAMID COMPANY (US) | 1983-10-12 | — | — | EP | disclosed |
| US-4281000-A | Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents | AMERICAN CYANAMID COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| EP-0027390-A1 | Novel benzodiazepine compounds, their preparation, intermediates employed in their preparation, and pharmaceutical compositions containing them | Lilly Industries Limited (GB) | 1981-04-22 | — | — | EP | disclosed |
| EP-0025819-A1 | Substituted pyrazolo (1,5-a) pyrimidines, and their preparation | AMERICAN CYANAMID COMPANY (US) | 1981-04-01 | — | — | EP | disclosed |