SCHEMBL4361606

SCHEMBL4361606

Cc1n[nH]c(C)c1C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15556607 0.78
SCHEMBL1923507 0.76
SCHEMBL4350923 0.76
SCHEMBL163701 0.76
SCHEMBL4358069 0.76
SCHEMBL19120698 0.73 DYRK1A (0.44)
SCHEMBL24610542 0.73 DHODH (0.47)
SCHEMBL16404451 0.73 DHODH (0.57)
SCHEMBL24610541 0.73 DHODH (0.41)
SCHEMBL13163178 0.72 DHODH (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492193-B2 Pyrazole derivatives for the treatment of cystic fibrosis FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) 2025-12-09 US claimed
US-12492193-B2 Pyrazole derivatives for the treatment of cystic fibrosis FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) 2025-12-09 US disclosed
EP-4341247-A1 RIP1 MODULATORS INCLUDING AZETIDINE CYCLIC UREAS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2024-03-27 EP disclosed
CN-117355506-A RIP1 modulators comprising azetidine cyclic ureas, preparation and use thereof 维泰瑞隆有限公司 2024-01-05 CN disclosed
US-11786575-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-17 US disclosed
US-11786575-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-17 US disclosed
US-11786575-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-17 US disclosed
CN-111741956-B Antiparasitic depsipeptides 硕腾服务有限责任公司 2023-07-07 CN disclosed
US-20230212157-A1 PYRAZOLE DERIVATIVES FOR THE TREATMENT OF CYSTIC FIBROSIS ISTITUTO GIANNINA GASLINI (IT) 2023-07-06 US disclosed
US-11597723-B2 Pyrazole derivatives for the treatment of cystic fibrosis FONDAZIONE ISTITUTO ITALIANO DI TECHNOLOGIA (IT) 2023-03-07 US disclosed
US-7533978-B2 Color composition and inkjet recording method FUJIFILM CORPORATION (JP) 2009-05-19 US disclosed
US-7533978-B2 Color composition and inkjet recording method FUJIFILM CORPORATION (JP) 2009-05-19 US disclosed
US-20080217617-A1 Thin Film Transistor, Wiring Board and Methods of Manufacturing the Same ZEON CORPORATION (JP) 2008-09-11 US disclosed
CN-100383278-C Partial plating method, partially-plated resin base, method for manufacturing multilayer circuit board ZEON CORP (JP) 2008-04-23 CN disclosed
US-7192475-B2 colored materials having good hue, excellent fastness to light and active gases in the circumstance, particularly an ozone gas, and high printing density FUJI PHOTO FILM CO., LTD. (JP) 2007-03-20 US disclosed
US-7192475-B2 colored materials having good hue, excellent fastness to light and active gases in the circumstance, particularly an ozone gas, and high printing density FUJI PHOTO FILM CO., LTD. (JP) 2007-03-20 US disclosed
US-20050153059-A1 Partial plating method, partially-plated resin base, method for manufacturing multilayered circuit board ZEON CORPORATION (JP) 2005-07-14 US disclosed
CN-1639384-A Partial plating method, partially-plated resin base, method for manufacturing multilayer circuit board ZEON CORP (JP) 2005-07-13 CN disclosed
US-20040237295-A1 Multilayer circuit board and resin base material, and its production method ZEON CORPORATION (JP) 2004-12-02 US disclosed
CN-1552174-A Mulitilayer circuit board, resin base material, and its production method �ձ�������ʽ���� 2004-12-01 CN disclosed