Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GLI1 | P08151 | 1/20 | 0.31 |
| ▸ | F9 | P00740 | 1/20 | 0.31 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16407827 | 1.00 | F10 (0.41) | F10POLBCYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL16370301 | 0.82 | F10 (0.34) | F10CYP2C19ALDH1A1CYP2C9MAPK1 | |
| SCHEMBL16391350 | 0.79 | F10 (0.44) | F10POLBPTPN2PTPN1CDC25B | |
| SCHEMBL16409181 | 0.78 | LMNA (0.33) | F10POLBCYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL22484370 | 0.74 | CYP2C19 (0.35) | F10POLBCYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL16407828 | 0.74 | CYP2C9 (0.50) | F10POLBCYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL27634524 | 0.73 | F10 (0.50) | F10POLBPTPN2PTPN1CDC25B | |
| SCHEMBL16391387 | 0.73 | F10 (0.50) | F10POLBPTPN2PTPN1CDC25B | |
| SCHEMBL20221633 | 0.73 | F10 (0.50) | F10POLBPTPN2PTPN1CDC25B | |
| SCHEMBL16214712 | 0.72 | F10 (0.49) | F10ALDH1A1CYP3A4CYP2C9PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770439-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-26 | — | — | US | disclosed |
| EP-3019196-A1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2016-05-18 | — | — | EP | disclosed |
| WO-2015005901-A1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-01-15 | — | — | WO | disclosed |