SCHEMBL16371002

SCHEMBL16371002

CCCCCCCCCC(N)CCCCCCCC(C)C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G1B P04054 1/20 0.59
PLA2G2A P14555 1/20 0.59
OPRM1 P35372 1/20 0.56
S1PR2 O95136 5/20 0.53
S1PR1 P21453 5/20 0.53
S1PR3 Q99500 5/20 0.53
S1PR4 O95977 4/20 0.53
SPHK1 Q9NYA1 2/20 0.52
ALDH1A1 P00352 1/20 0.45
TP53 P04637 2/20 0.45
LMNA P02545 3/20 0.43
CYP2D6 P10635 2/20 0.43
GMNN O75496 1/20 0.43
POLB P06746 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
BLM P54132 1/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28977213 1.00 PLA2G1B (0.59) PLA2G1BPLA2G2AOPRM1S1PR2S1PR1
SCHEMBL21161889 1.00 PLA2G1B (0.59) PLA2G1BPLA2G2AOPRM1S1PR2S1PR1
SCHEMBL15319803 1.00 PLA2G1B (0.59) PLA2G1BPLA2G2AOPRM1S1PR2S1PR1
SCHEMBL15054363 1.00 PLA2G1B (0.59) PLA2G1BPLA2G2AOPRM1S1PR2S1PR1
SCHEMBL18298232 1.00 PLA2G1B (0.59) PLA2G1BPLA2G2AOPRM1S1PR2S1PR1
SCHEMBL28446507 1.00 PLA2G1B (0.59) PLA2G1BPLA2G2AOPRM1S1PR2S1PR1
SCHEMBL21161890 0.95 PLA2G1B (0.54) PLA2G1BPLA2G2AOPRM1S1PR2S1PR1
SCHEMBL29186627 0.93 PLA2G1B (0.57) PLA2G1BPLA2G2AOPRM1S1PR2S1PR1
SCHEMBL6281344 0.93 PLA2G1B (0.57) PLA2G1BPLA2G2AOPRM1S1PR2S1PR1
SCHEMBL6279840 0.93 PLA2G1B (0.57) PLA2G1BPLA2G2AOPRM1S1PR2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4637786-A2 SMALL NUCLEAR RIBONUCLEOPROTEIN 13 POLYPEPTIDES, POLYNUCLEOTIDES, AND USES THEREOF ModernaTX, Inc. (US) 2025-10-29 EP disclosed
EP-4634388-A1 COMPOSITIONS AND METHODS FOR INFECTIOUS DISEASES Providence Therapeutics Holdings Inc. (CA) 2025-10-22 EP disclosed
US-12403177-B2 Silk-based product formulations and methods of use COCOON BIOTECH INC. (US) 2025-09-02 US disclosed
WO-2025061153-A1 RNA-LIPID PARTICLES COMPRISING POLYSARCOSINE-LIPID CONJUGATE Everest Medicines (China) Co., Ltd. (CN) 2025-03-27 WO disclosed
EP-4522646-A2 APOE LIPOPROTEIN SYSTEMS Kisbee Therapeutics, Inc. (US) 2025-03-19 EP disclosed
EP-4452928-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF Renagade Therapeutics Management Inc. (US) 2024-10-30 EP disclosed
EP-4402123-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF Renagade Therapeutics Management Inc. (US) 2024-07-24 EP disclosed
WO-2024137953-A2 SMALL NUCLEAR RIBONUCLEOPROTEIN 13 POLYPEPTIDES, POLYNUCLEOTIDES, AND USES THEREOF MODERNATX, INC. (US) 2024-06-27 WO disclosed
WO-2024026257-A2 ENGINEERED POLYNUCLEOTIDES FOR CELL SELECTIVE EXPRESSION MODERNATX, INC. (US) 2024-02-01 WO disclosed
WO-2024026254-A1 ENGINEERED POLYNUCLEOTIDES FOR TEMPORAL CONTROL OF EXPRESSION MODERNATX, INC. (US) 2024-02-01 WO disclosed
WO-2023023055-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING TROPISM OF DELIVERY SYSTEMS FOR RNA RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-02-23 WO disclosed
EP-3801625-A1 SILK-BASED PRODUCT FORMULATIONS AND METHODS OF USE Cocoon Biotech Inc. (US) 2021-04-14 EP disclosed
US-10821175-B2 Lipid nanoparticle vaccine adjuvants and antigen delivery systems MERCK SHARP & DOHME CORP. (US) 2020-11-03 US disclosed
EP-3365007-A2 BROAD SPECTRUM INFLUENZA VIRUS VACCINE ModernaTX, Inc. (US) 2018-08-29 EP disclosed
WO-2017070620-A2 BROAD SPECTRUM INFLUENZA VIRUS VACCINE MODERNATX, INC. (US) 2017-04-27 WO disclosed
US-20160361411-A1 LIPID NANOPARTICLE VACCINE ADJUVANTS AND ANTIGEN DELIVERY SYSTEMS MERCK SHARP & DOHME CORP (US) 2016-12-15 US disclosed
EP-3076994-A2 TARGETED ADAPTIVE VACCINES Moderna Therapeutics, Inc. (US) 2016-10-12 EP disclosed
EP-3019619-A2 COMPOSITIONS COMPRISING SYNTHETIC POLYNUCLEOTIDES ENCODING CRISPR RELATED PROTEINS AND SYNTHETIC SGRNAS AND METHODS OF USE Moderna Therapeutics, Inc. (US) 2016-05-18 EP disclosed
WO-2015085318-A2 TARGETED ADAPTIVE VACCINES MODERNA THERAPEUTICS, INC. (US) 2015-06-11 WO disclosed
WO-2015006747-A2 COMPOSITIONS COMPRISING SYNTHETIC POLYNUCLEOTIDES ENCODING CRISPR RELATED PROTEINS AND SYNTHETIC SGRNAS AND METHODS OF USE. MODERNA THERAPEUTICS, INC. (US) 2015-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10821175-B2 Lipid nanoparticle vaccine adjuvants and antigen delivery systems TLR3, TLR5, TLR1 PLA2G1B 176/4885PLA2G2A 101/4885OPRM1 3751/4885
US-20160361411-A1 LIPID NANOPARTICLE VACCINE ADJUVANTS AND ANTIGEN DELIVERY SYSTEMS TLR3, TLR5, TLR1 PLA2G1B 176/4885PLA2G2A 101/4885OPRM1 3751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.