Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16370581 | 1.00 | L3MBTL1 (0.71) | L3MBTL1SMN1; SMN2MAPK1GAAKMT2A | |
| SCHEMBL16370714 | 1.00 | L3MBTL1 (0.71) | L3MBTL1SMN1; SMN2MAPK1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL16371042 | 0.99 | MAPK1 (0.72) | L3MBTL1SMN1; SMN2MAPK1GAAKMT2A | |
| SCHEMBL22639809 | 0.89 | L3MBTL1 (0.67) | L3MBTL1SMN1; SMN2MAPK1GAAKMT2A | |
| SCHEMBL22639911 | 0.89 | L3MBTL1 (0.67) | L3MBTL1SMN1; SMN2MAPK1GAAKMT2A | |
| SCHEMBL4578170 | 0.86 | USP2 (0.83) | L3MBTL1SMN1; SMN2MAPK1GAAKMT2A | |
| SCHEMBL12834994 | 0.85 | USP2 (0.81) | L3MBTL1SMN1; SMN2MAPK1GAAKMT2A | |
| SCHEMBL4578593 | 0.83 | L3MBTL1 (1.00) | L3MBTL1SMN1; SMN2MAPK1GAAKMT2A | |
| SCHEMBL24355399 | 0.83 | KDM4E (0.68) | L3MBTL1SMN1; SMN2KMT2AMAPTUSP2 | |
| SCHEMBL19182544 | 0.83 | KDM4E (0.68) | L3MBTL1SMN1; SMN2KMT2AMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015004485-A1 | THERAPEUTIC COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-01-15 | — | — | WO | disclosed |
| WO-2015004485-A1 | THERAPEUTIC COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-01-15 | — | — | WO | disclosed |