Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | VHL | P40337 | 1/20 | 0.40 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12133623 | 0.78 | KMT2A (0.76) | KMT2AHDAC1HDAC6ALDH1A1MAPT | |
| SCHEMBL18259814 | 0.78 | NR1H4 (0.57) | KMT2AHDAC1HDAC6ALDH1A1HDAC3 | |
| SCHEMBL21153197 | 0.76 | MAOA (0.63) | HDAC1HDAC6ALDH1A1MAPTPOLB | |
| SCHEMBL469040 | 0.75 | HTR2C (0.58) | KMT2AHDAC1HDAC6ALDH1A1MAPT | |
| SCHEMBL18259873 | 0.75 | NPC1 (0.58) | KMT2AALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL13414995 | 0.75 | SMN1; SMN2 (0.52) | KMT2AALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL15772961 | 0.74 | CYP4F2 (0.51) | ALDH1A1MAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL10188221 | 0.72 | HTR2C (0.51) | KMT2AHDAC1HDAC6ALDH1A1MAPT | |
| SCHEMBL1429353 | 0.72 | SMN1; SMN2 (0.56) | KMT2AALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL21153196 | 0.71 | MEN1 (0.45) | KMT2AHDAC6HTR2CHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278905-B2 | Production method for compound comprising amino group and/or hydroxyl group | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2016-03-08 | — | — | US | disclosed |
| US-9278905-B2 | Production method for compound comprising amino group and/or hydroxyl group | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2016-03-08 | — | — | US | disclosed |
| US-20150105559-A1 | PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2015-04-16 | — | — | US | disclosed |
| US-20150105559-A1 | PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2015-04-16 | — | — | US | disclosed |
| EP-2821389-A1 | PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP | Kyushu University, National University Corporation (JP) | 2015-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105559-A1 | PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP | CA7, DAO, CA4 | KMT2A 837/4885HDAC1 638/4885HDAC6 1322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.