Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | TK1 | P04183 | 2/20 | 0.41 |
| ▸ | PNP | P00491 | 2/20 | 0.40 |
| ▸ | HINT1 | P49773 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15833027 | 1.00 | ADORA3 (0.49) | ADORA3TK1PNPHINT1NT5E | |
| SCHEMBL15833130 | 0.90 | ADORA3 (0.48) | ADORA3TK1PNPHINT1NT5E | |
| SCHEMBL15833211 | 0.90 | ADORA3 (0.48) | ADORA3TK1PNPHINT1NT5E | |
| SCHEMBL15837491 | 0.90 | ADORA3 (0.46) | ADORA3TK1PNPHINT1USP2 | |
| SCHEMBL15837260 | 0.89 | ADORA3 (0.37) | ADORA3HINT1 | |
| SCHEMBL31228276 | 0.87 | ADORA3 (0.53) | ADORA3TK1PNPHINT1NT5E | |
| SCHEMBL15833215 | 0.85 | ADORA3 (0.52) | ADORA3TK1PNPHINT1NT5E | |
| SCHEMBL15837295 | 0.85 | ADORA3 (0.52) | ADORA3TK1PNPHINT1NT5E | |
| SCHEMBL18877390 | 0.85 | ADORA3 (0.52) | ADORA3TK1PNPHINT1NT5E | |
| SCHEMBL15833217 | 0.85 | ADORA3 (0.52) | ADORA3TK1PNPHINT1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054465-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2015-04-16 | — | — | WO | disclosed |
| WO-2014209979-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2014-12-31 | — | — | WO | disclosed |