Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23191095 | 0.78 | ALDH1A1 (0.60) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL13397481 | 0.77 | TSHR (0.39) | TSHR | |
| SCHEMBL8499269 | 0.76 | TSHR (0.38) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL22211120 | 0.76 | TSHR (0.45) | TSHR | |
| SCHEMBL65142 | 0.76 | TSHR (0.45) | TSHR | |
| SCHEMBL20259984 | 0.73 | TSHR (0.32) | TSHR | |
| SCHEMBL17703945 | 0.70 | TSHR (0.41) | TSHR | |
| SCHEMBL28964667 | 0.68 | — | — | |
| SCHEMBL23019939 | 0.68 | TSHR (0.56) | TSHRALDH1A1 | |
| SCHEMBL22212777 | 0.67 | TSHR (0.37) | TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2821430-A1 | Siloxane polymers with central polysiloxane polymer block with organofunctional residues, each comprising at least two bivalent groups selected from urea and/or carbamate groups and at least one UV/Vis chromophore as residue | Evonik Industries AG (DE) | 2015-01-07 | — | — | EP | disclosed |