Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17589584 | 0.97 | NPSR1 (0.42) | NPSR1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL805321 | 0.92 | NPSR1 (0.47) | NPSR1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL801103 | 0.91 | KDM4E (0.42) | NPSR1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL801196 | 0.88 | NPSR1 (0.38) | NPSR1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL801163 | 0.88 | NPSR1 (0.38) | NPSR1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL801718 | 0.88 | KDM4E (0.47) | NPSR1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL29512082 | 0.88 | KDM4E (0.47) | NPSR1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL801093 | 0.88 | KDM4E (0.47) | NPSR1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL801131 | 0.87 | KDM4E (0.50) | NPSR1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL801193 | 0.87 | NPSR1 (0.37) | NPSR1MAPTKDM4EKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2436751-B1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | SK CHEMICALS CO LTD (KR) | 2015-01-07 | — | — | EP | disclosed |