Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL801196 | 0.99 | NPSR1 (0.38) | NPSR1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL801600 | 0.93 | PPARG (0.39) | NPSR1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL801335 | 0.91 | PPARG (0.39) | NPSR1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL801604 | 0.89 | PPARG (0.38) | NPSR1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL801164 | 0.89 | PPARG (0.41) | NPSR1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL805321 | 0.87 | NPSR1 (0.47) | NPSR1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL16374929 | 0.87 | NPSR1 (0.42) | NPSR1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL11991162 | 0.85 | MAT2A (0.41) | NPSR1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL17589584 | 0.84 | NPSR1 (0.42) | NPSR1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL801103 | 0.84 | KDM4E (0.42) | NPSR1MAPTKDM4ESMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278986-B2 | Carbazole-based phosphine oxide compound, and organic electroluminescent device including the same | SK CHEMICALS CO., LTD. (KR) | 2016-03-08 | — | — | US | disclosed |
| US-9278986-B2 | Carbazole-based phosphine oxide compound, and organic electroluminescent device including the same | SK CHEMICALS CO., LTD. (KR) | 2016-03-08 | — | — | US | disclosed |
| EP-2436751-B1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | SK CHEMICALS CO LTD (KR) | 2015-01-07 | — | — | EP | disclosed |
| US-20120068168-A1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) | 2012-03-22 | — | — | US | disclosed |
| US-20120068168-A1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120068168-A1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | INPP5B, EZH2, PLCB3 | NPSR1 4411/4885MAPT 2464/4885KDM4E 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.