Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK5 | O95279 | 1/20 | 0.41 |
| ▸ | KCNK17 | Q96T54 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15978569 | 0.89 | MET (0.43) | METKCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL16375007 | 0.77 | MET (0.46) | METKCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL16374956 | 0.77 | PPARD (0.46) | METKCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL8981574 | 0.76 | CNR2 (0.52) | FAAHCNR2 | |
| SCHEMBL16374958 | 0.76 | KCNK3 (0.44) | METKCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL15015195 | 0.75 | PDE10A (0.42) | METKCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL92991 | 0.75 | CNR2 (0.49) | FAAHCNR2 | |
| SCHEMBL19625793 | 0.73 | KCNA5 (0.52) | METKCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL2601314 | 0.71 | PDE10A (0.49) | METKCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL15015194 | 0.70 | PDE10A (0.43) | METKCNA5KCNK3KCNK5KCNK17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015001572-A2 | PROCESS FOR THE PREPARATION OF INTERMEDIATE OF DOLUTEGRAVIR | HETERO RESEARCH FOUNDATION (IN) | 2015-01-08 | — | — | WO | disclosed |