SCHEMBL16375340

SCHEMBL16375340

O=C1CCCCC1C(Nc1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 10/20 1.00
MAPT P10636 3/20 0.82
KDM4E B2RXH2 2/20 0.82
HPGD P15428 2/20 0.82
LMNA P02545 2/20 0.82
SMN1; SMN2 Q16637 1/20 0.82
NPSR1 Q6W5P4 1/20 0.82
CA2 P00918 1/20 0.48
ALDH1A1 P00352 2/20 0.43
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
RAB9A P51151 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.42
HTR1E P28566 1/20 0.42
KMT2A Q03164 1/20 0.42
S1PR3 Q99500 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27929593 0.95 CA1 (0.91) CA1MAPTKDM4EHPGDLMNA
SCHEMBL28015291 0.90 CA1 (0.82) CA1MAPTKDM4EHPGDLMNA
SCHEMBL28015297 0.90 MAPT (0.90) CA1MAPTKDM4EHPGDLMNA
SCHEMBL28317423 0.90 CA1 (0.82) CA1MAPTKDM4EHPGDLMNA
SCHEMBL29065875 0.90 CA1 (0.82) CA1MAPTKDM4EHPGDLMNA
SCHEMBL29065872 0.90 MAPT (0.90) CA1MAPTKDM4EHPGDLMNA
SCHEMBL30530181 0.88 CA1 (0.78) CA1MAPTKDM4EHPGDLMNA
SCHEMBL29065863 0.88 CA1 (0.78) CA1MAPTKDM4EHPGDLMNA
SCHEMBL30530180 0.88 CA1 (0.78) CA1MAPTKDM4EHPGDLMNA
SCHEMBL29065861 0.87 CA1 (0.76) CA1MAPTKDM4EHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024365-B Pyrazole ionic liquid and method for catalyzing Mannich reaction by using same 山西师范大学 2025-06-24 CN claimed
CN-117024365-A Pyrazole ionic liquid and method for catalyzing Mannich reaction by using same 山西师范大学 2023-11-10 CN claimed
CN-117024365-B Pyrazole ionic liquid and method for catalyzing Mannich reaction by using same 山西师范大学 2025-06-24 CN disclosed
CN-116715596-B Method for synthesizing beta-aminoketone compound by synergistic catalysis of cyclopentadienyl titanium/Bronsted acid 宁夏师范学院 2025-01-14 CN disclosed
CN-117024365-A Pyrazole ionic liquid and method for catalyzing Mannich reaction by using same 山西师范大学 2023-11-10 CN disclosed
CN-116715596-A Method for synthesizing beta-aminoketone compound by synergistic catalysis of cyclopentadienyl titanium/Bronsted acid 宁夏师范学院 2023-09-08 CN disclosed
US-20200290267-A1 Three-Dimensional Printing of Impregnated Plastics for Chemical Reactions UCL BUSINESS PLC (GB) 2020-09-17 US disclosed
EP-3430473-A1 THREE-DIMENSIONAL PRINTING OF IMPREGNATED PLASTICS FOR CHEMICAL REACTIONS UCL Business Plc. (GB) 2019-01-23 EP disclosed
CN-109073966-A The chemical reaction 3 D-printing of impregnated plastic UCL商业有限公司 2018-12-21 CN disclosed
WO-2015000543-A1 RARE EARTH METAL-BIS(PERFLUOROALKYL)PHOSPHINATES AS LEWIS ACID CATALYSTS MERCK PATENT GMBH (DE) 2015-01-08 WO disclosed