Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.82 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29065875 | 0.95 | CA1 (0.82) | CA1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL16375340 | 0.90 | CA1 (1.00) | CA1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29065873 | 0.87 | MAPT (0.77) | CA1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28317423 | 0.87 | CA1 (0.82) | CA1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29065872 | 0.87 | MAPT (0.90) | CA1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28015297 | 0.87 | MAPT (0.90) | CA1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28318413 | 0.86 | CA1 (0.76) | CA1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL27929593 | 0.86 | CA1 (0.91) | CA1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29065865 | 0.83 | CA1 (0.76) | CA1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL30530181 | 0.82 | CA1 (0.78) | CA1MAPTKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106861757-B | A kind of organic boron of fluorescent marker/nitrogen lewis acid base bifunctional catalyst and preparation method thereof | 湖南大学 | 2019-08-09 | — | — | CN | disclosed |
| CN-104529796-A | Catalytic synthesis application based on frustrated Lewis acid-base pair | UNIV HUNAN | 2015-04-22 | — | — | CN | disclosed |