Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462101 | 0.86 | GAA (0.40) | ALDH1A1GAACYP3A4 | |
| SCHEMBL1043332 | 0.80 | CES2 (0.36) | ALDH1A1CYP3A4CES2CES1 | |
| SCHEMBL1041423 | 0.79 | CYP3A4 (0.39) | ALDH1A1GAACYP3A4 | |
| Phosphine SCHEMBL28192224 | 0.77 | CES2 (0.35) | ALDH1A1CYP3A4CES2CES1 | |
| Hydrogen Sulfide SCHEMBL28335379 | 0.77 | CES2 (0.35) | ALDH1A1CYP3A4CES2CES1 | |
| SCHEMBL8873189 | 0.76 | GAA (0.36) | ALDH1A1GAACYP3A4 | |
| SCHEMBL23205852 | 0.75 | CD44 (0.41) | ALDH1A1GAACYP3A4 | |
| SCHEMBL1494369 | 0.75 | GAA (0.34) | ALDH1A1GAA | |
| SCHEMBL9153454 | 0.74 | GRIN2D (0.36) | ALDH1A1GAACYP3A4 | |
| Hydrochloric Acid SCHEMBL1494535 | 0.73 | GAA (0.33) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497213-B1 | Process for producing 3,5-difluoroaniline | ISHIHARA SANGYO KAISHA (JP) | 1995-09-27 | — | — | EP | claimed |
| US-5399767-A | Process for producing 3,5-difluoraniline | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-03-21 | — | — | US | claimed |
| EP-0497213-A2 | Process for producing 3,5-difluoroaniline | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-08-05 | — | — | EP | claimed |
| JP-5246958-A | — | — | None | — | — | JP | disclosed |
| JP-5065250-A | — | — | None | — | — | JP | disclosed |
| EP-3532474-B1 | 4,5-ANNULATED 1,2,4-TRIAZOLONES | BAYER AG (DE) | 2024-03-27 | — | — | EP | disclosed |
| CN-114921391-B | 4, 5-cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2024-01-02 | — | — | CN | disclosed |
| US-11787797-B2 | 4,5-annulated 1,2,4-triazolones | BAYER AKTIENGESELLSCHAFT (DE) | 2023-10-17 | — | — | US | disclosed |
| CN-114921391-A | 4, 5-Cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-110248937-B | 4, 5-Cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-108250199-B | Dihydropyridone P1 as factor XIA inhibitor | 百时美施贵宝公司 | 2021-07-16 | — | — | CN | disclosed |
| US-5510533-A | Process for producing 3,5-difluoroaniline and derivative thereof | SDS BIOTECH K.K. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0460639-B1 | Process for producing 3,5-difluoroaniline and derivative thereof | SDS BIOTECH CORP (JP) | 1995-12-27 | — | — | EP | disclosed |
| EP-0497213-B1 | Process for producing 3,5-difluoroaniline | ISHIHARA SANGYO KAISHA (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5399767-A | Process for producing 3,5-difluoraniline | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0596130-A1 | PRODUCTION OF 2-HALO-3,5-DIFLUOROANILINE, INTERMEDIATE FOR PRODUCING THE SAME, AND PRODUCTION OF SAID INTERMEDIATE | SDS Biotech K.K. (JP) | 1994-05-11 | — | — | EP | disclosed |
| JP-H05246958-A | PRODUCTION OF 3,5-DIFLUROANILINE | SDS BIOTECH KK | 1993-09-24 | — | — | JP | disclosed |
| JP-H0565250-A | PRODUCTION OF 3,5-DIFLUOROANILINE | ISHIHARA SANGYO KAISHA LTD | 1993-03-19 | — | — | JP | disclosed |
| EP-0497213-A2 | Process for producing 3,5-difluoroaniline | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-08-05 | — | — | EP | disclosed |
| EP-0460639-A1 | Process for producing 3,5-difluoroaniline and derivative thereof | SDS Biotech K.K. (JP) | 1991-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787797-B2 | 4,5-annulated 1,2,4-triazolones | CCNA1, CCNT1, CCND2 | ALDH1A1 274/4885GAA 1917/4885CYP3A4 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.