Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16376636 | 0.91 | HRH3 (0.33) | KDM1AHRH3ALDH1A1CYP2D6 | |
| SCHEMBL16376650 | 0.88 | KDM1A (0.32) | KDM1AHRH3ALDH1A1CYP2D6 | |
| SCHEMBL16376628 | 0.83 | DRD2 (0.35) | — | |
| SCHEMBL839914 | 0.83 | KDM1A (0.33) | KDM1AHRH3ALDH1A1CYP2D6 | |
| SCHEMBL18269017 | 0.78 | — | — | |
| SCHEMBL18269020 | 0.78 | — | — | |
| SCHEMBL840364 | 0.78 | HRH3 (0.34) | KDM1AHRH3ALDH1A1CYP2D6 | |
| SCHEMBL18269027 | 0.78 | HRH3 (0.33) | KDM1AHRH3ALDH1A1CYP2D6 | |
| SCHEMBL16376639 | 0.78 | KAT2B (0.31) | HRH3CYP2D6 | |
| SCHEMBL841019 | 0.77 | HRH3 (0.35) | KDM1AHRH3ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9193714-B2 | Fluorinated estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS, INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20150005286-A1 | FLUORINATED ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | SERAGON PHARMACEUTICALS, INC. | 2015-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005286-A1 | FLUORINATED ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | GPER1, ESR2, ESRRG | KDM1A 2535/4885HRH3 1352/4885ALDH1A1 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.