SCHEMBL16377232

SCHEMBL16377232

CCCc1ccc(-c2ccc(-c3ccc(CC)c(F)c3F)c(F)c2F)cc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MPL P40238 7/20 0.43
CTSL P07711 1/20 0.42
CTSS P25774 1/20 0.42
CTSK P43235 1/20 0.42
CHKA P35790 1/20 0.41
RARB P10826 2/20 0.39
ALOX5 P09917 1/20 0.36
CA2 P00918 1/20 0.36
MCL1 Q07820 1/20 0.36
LPL P06858 1/20 0.34
LIPG Q9Y5X9 1/20 0.34
MGLL Q99685 1/20 0.34
PLK1 P53350 1/20 0.34
NISCH Q9Y2I1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17614871 0.98 CHKA (0.42) MPLCTSLCTSSCTSKCHKA
SCHEMBL9486711 0.97 CHKA (0.41) MPLCTSLCTSSCTSKCHKA
SCHEMBL16377213 0.97 CHKA (0.41) MPLCTSLCTSSCTSKCHKA
SCHEMBL12735528 0.94 CTSL (0.40) MPLCTSLCTSSCTSKCHKA
SCHEMBL12740082 0.94 CTSL (0.40) MPLCTSLCTSSCTSKCHKA
SCHEMBL16377235 0.92 CTSL (0.46) MPLCTSLCTSSCTSKCHKA
SCHEMBL10301912 0.90 CTSL (0.43) MPLCTSLCTSSCTSKCHKA
SCHEMBL10301915 0.90 CTSL (0.43) MPLCTSLCTSSCTSKCHKA
SCHEMBL9563683 0.90 CTSL (0.43) MPLCTSLCTSSCTSKCHKA
SCHEMBL16377230 0.90 RARB (0.46) MPLCTSLCTSSCTSKCHKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9321960-B2 Nematic liquid crystal composition and liquid crystal display device using same DIC Corporation (Tokyo) (JP) 2016-04-26 US disclosed
US-9321960-B2 Nematic liquid crystal composition and liquid crystal display device using same DIC Corporation (Tokyo) (JP) 2016-04-26 US disclosed
US-20150001444-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-01-01 US disclosed
US-20150001444-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-01-01 US disclosed