SCHEMBL1637751

SCHEMBL1637751

CCCc1cc[c]c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
SKP2 Q13309 1/20 0.37
NPC1 O15118 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
ALOX5 P09917 1/20 0.33
CA2 P00918 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
DRD2 P14416 1/20 0.30
DRD1 P21728 1/20 0.30
DRD4 P21917 1/20 0.30
DRD5 P21918 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1741603 0.89 SKP2 (0.48) SKP2NPC1HPGDMAPK1HTT
SCHEMBL6885851 0.86 SKP2 (0.46) SKP2NPC1HPGDMAPK1HTT
SCHEMBL11384499 0.84 SKP2 (0.44) SKP2NPC1HPGDMAPK1HTT
SCHEMBL10527233 0.84 SKP2 (0.44) SKP2NPC1HPGDMAPK1HTT
SCHEMBL28108936 0.84 SKP2 (0.44) SKP2NPC1HPGDMAPK1HTT
SCHEMBL455762 0.82
SCHEMBL25262266 0.81 KDM4E (0.42) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL7957864 0.81 TDP1 (0.38) SKP2
SCHEMBL15067323 0.80 CNR1 (0.42) CNR1CNR2SKP2LPLLIPG
SCHEMBL8902334 0.79 ESR1 (0.38) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3752494-A1 REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METATHESIS CATALYSTS UMICORE AG & Co. KG (DE) 2020-12-23 EP claimed
WO-2019158485-A1 REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METATHESIS CATALYSTS UMICORE AG & CO. KG (DE) 2019-08-22 WO claimed
EP-3503999-A1 SYNTHESIS AND CHARACTERIZATION OF METATHESIS CATALYSTS UMICORE AG & CO. KG (DE) 2019-07-03 EP claimed
EP-3496855-A1 METATHESIS CATALYSTS UMICORE AG & CO. KG (DE) 2019-06-19 EP claimed
WO-2018038928-A1 SYNTHESIS AND CHARACTERIZATION OF METATHESIS CATALYSTS MATERIA, INC. (US) 2018-03-01 WO claimed
WO-2018034931-A1 METATHESIS CATALYSTS MATERIA, INC. (US) 2018-02-22 WO claimed
WO-2014107447-A1 FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2014-07-10 WO claimed
EP-2170864-B1 PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS BRISTOL MYERS SQUIBB CO (US) 2011-09-14 EP claimed
EP-3607002-A1 COLORANT MIXTURES Huntsman Advanced Materials (Switzerland) GmbH (CH) 2020-02-12 EP disclosed
WO-2019179773-A1 DIACETAL DERIVATIVES AND THEIR USE AS CLARIFIER CLARIANT INTERNATIONAL LTD (CH) 2019-09-26 WO disclosed
EP-3543244-A1 DIACETAL DERIVATIVES AND THEIR USE AS CLARIFIER Clariant International Ltd (CH) 2019-09-25 EP disclosed
EP-3543286-A1 POLYMER COMPOSITION COMPRISING DIACETAL DERIVATIVES Clariant International Ltd (CH) 2019-09-25 EP disclosed
EP-3503999-A1 SYNTHESIS AND CHARACTERIZATION OF METATHESIS CATALYSTS UMICORE AG & CO. KG (DE) 2019-07-03 EP disclosed
EP-3496855-A1 METATHESIS CATALYSTS UMICORE AG & CO. KG (DE) 2019-06-19 EP disclosed
US-20050209253-A1 Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group TAISHO PHARMACEUTICAL CO., LTD. (JP) 2005-09-22 US disclosed
EP-1467997-A1 PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP Taisho Pharmaceutical Co. Ltd. (JP) 2004-10-20 EP disclosed
WO-2004058767-A1 PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP TAISHO PHARMACEUTICAL CO., LTD. (JP) 2004-07-15 WO disclosed
CN-1174205-A Carrier catalyst system, its prep, and use in polymerization of olefines thereof HOECHST AG (DE) 1998-02-25 CN disclosed
US-4713186-A PHOSPHATE AND GRAPHITE OR INTERCALATION COMPOUND LONZA LTD. (CH) 1987-12-15 US disclosed
US-3950374-A INSECTICIDE, NEMATOCIDE, MITICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209253-A1 Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group HRH2, HRH4, HRH1 CNR1 40/4885CNR2 37/4885SKP2 925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.