Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696001 | 1.00 | CHRNA7 (0.54) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL1696003 | 1.00 | CHRNA7 (0.54) | CHRNA7BCHEACHECHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL2485785 | 0.99 | CHRNA7 (0.53) | CHRNA7BCHEACHECHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL2485787 | 0.99 | CHRNA7 (0.53) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL19894805 | 0.90 | CHRM3 (0.47) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL12071819 | 0.84 | CHRM3 (0.62) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL1695935 | 0.84 | CHRM3 (0.62) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL1695933 | 0.84 | CHRM3 (0.62) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL1695975 | 0.84 | CHRM3 (0.62) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL2486482 | 0.84 | CHRM3 (0.62) | CHRNA7BCHEACHECHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585458-B1 | Alkaloid aminoester derivatives and medicinal compositions thereof | CHIESI FARMA SPA (IT) | 2015-01-07 | — | — | EP | disclosed |