SCHEMBL1637792

SCHEMBL1637792

C1=C(N2CCOCC2)CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
PSMB5 P28074 1/20 0.39
ALDH1A1 P00352 8/20 0.37
LMNA P02545 7/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
PRKDC P78527 1/20 0.35
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
KDM4E B2RXH2 3/20 0.33
MAPT P10636 3/20 0.33
HTT P42858 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HPGD P15428 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7091842 1.00 CYP1A2 (0.40) CYP1A2CYP2D6CYP2C9CYP2C19PSMB5
SCHEMBL7091843 1.00 CYP1A2 (0.40) CYP1A2CYP2D6CYP2C9CYP2C19PSMB5
SCHEMBL7091840 1.00 CYP1A2 (0.40) CYP1A2CYP2D6CYP2C9CYP2C19PSMB5
SCHEMBL11746869 1.00 CYP1A2 (0.40) CYP1A2CYP2D6CYP2C9CYP2C19PSMB5
SCHEMBL11751485 1.00 CYP1A2 (0.40) CYP1A2CYP2D6CYP2C9CYP2C19PSMB5
SCHEMBL10738006 1.00 CYP1A2 (0.40) CYP1A2CYP2D6CYP2C9CYP2C19PSMB5
SCHEMBL10738011 1.00 CYP1A2 (0.40) CYP1A2CYP2D6CYP2C9CYP2C19PSMB5
SCHEMBL7143361 1.00 CYP1A2 (0.40) CYP1A2CYP2D6CYP2C9CYP2C19PSMB5
SCHEMBL150625 0.98 CYP1A2 (0.41) CYP1A2CYP2D6CYP2C9CYP2C19PSMB5
SCHEMBL497792 0.92 LMNA (0.39) CYP1A2CYP2D6CYP2C9CYP2C19PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
CN-110437295-A A kind of progesterone preparation method of high-efficiency low-pollution ZHEJIANG SHENZHOU PHARMACEUTICAL CO LTD 2019-11-12 CN disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7687067-B2 2-pyridinylcycloalkylcarboxamide derivatives useful as fungicides BAYER CROPSCIENCE S.A. (FR) 2010-03-30 US disclosed
US-7524968-B2 2-pyridinylcycloalkylbenzamide derivatives and their use as fungicides BAYER CROPSCIENCE S.A. (FR) 2009-04-28 US disclosed
US-7306884-B2 Dye-containing curable composition, color filter prepared using the same, and process of preparing color filter FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
US-7306884-B2 Dye-containing curable composition, color filter prepared using the same, and process of preparing color filter FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
EP-0085811-B1 2-(PHENYLMETHYLENE)CYCLOALKYLAMINES THE UPJOHN COMPANY (US) 1986-05-07 EP disclosed
US-4540690-A ANALGESICS, ANTIDEPRESSANTS THE UPJOHN COMPANY (US) 1985-09-10 US disclosed
EP-0138030-A2 Phenylethylamine derivatives F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-04-24 EP disclosed
EP-0111873-A1 Derivatives of cis, endo-2-azabicyclo-(5.3.0)-decane-3-carboxylic acid, process for their preparation, compositions containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1984-06-27 EP disclosed
EP-0085811-A1 2-(Phenylmethylene)cycloalkylamines THE UPJOHN COMPANY (US) 1983-08-17 EP disclosed
US-4167641-A HALOACYLATION, REACTION WITH ENAMINE AND TERT-AMINE, ACIDIFICATION TO FORM DIKETONE, REACTION WITH ALKALI METAL HYDROXIDE OR ALKOXIDE LANE AND EDSON, P. C. 1979-09-11 US disclosed
US-4048165-A Manufacture of 1-substituted oximino cyclo alkenes-(1) BASF AKTIENGESELLSCHAFT (DT) 1977-09-13 US disclosed