Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | PIK3R2 | O00459 | 3/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.31 |
| ▸ | PIK3R5 | Q8WYR1 | 3/20 | 0.31 |
| ▸ | PIK3R3 | Q92569 | 3/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16333638 | 0.89 | CCNA2 (0.39) | CCNA2CDK2CCNA1NR1H4PIK3CD | |
| SCHEMBL22626643 | 0.81 | CCNA2 (0.35) | CCNA2CDK2CCNA1NR1H4PIK3CD | |
| SCHEMBL16377700 | 0.80 | CCNA2 (0.37) | CCNA2CDK2CCNA1PIK3CDPIK3R2 | |
| SCHEMBL16377773 | 0.79 | CCNA2 (0.43) | CCNA2CDK2CCNA1CA1CA2 | |
| SCHEMBL16333930 | 0.79 | CCNA2 (0.37) | CCNA2CDK2CCNA1PIK3CDPIK3R2 | |
| SCHEMBL16377823 | 0.79 | CCNA2 (0.37) | CCNA2CDK2CCNA1PIK3CDPIK3R2 | |
| SCHEMBL16333609 | 0.78 | CCNA2 (0.39) | CCNA2CDK2CCNA1PIK3CDPIK3R2 | |
| SCHEMBL16339733 | 0.78 | CCNA2 (0.36) | CCNA2CDK2CCNA1NR1H4PIK3CD | |
| SCHEMBL29670696 | 0.78 | CCNA2 (0.36) | CCNA2CDK2CCNA1NR1H4PIK3CD | |
| SCHEMBL22607657 | 0.78 | CCNA2 (0.37) | CCNA2CDK2CCNA1PIK3CDPIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014209980-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2014-12-31 | — | — | WO | disclosed |