Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 6/20 | 0.35 |
| ▸ | CDK2 | P24941 | 6/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.31 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16333638 | 0.93 | CCNA2 (0.39) | CCNA2CDK2CCNA1TGFBR1ACVR1 | |
| SCHEMBL16377773 | 0.89 | CCNA2 (0.43) | CCNA2CDK2CCNA1MAPTPOLB | |
| SCHEMBL22626591 | 0.88 | CCNA2 (0.34) | CCNA2CDK2CCNA1TGFBR1ACVR1 | |
| SCHEMBL29539301 | 0.87 | PDE7A (0.32) | NR1H4 | |
| SCHEMBL16334006 | 0.87 | PDE7A (0.32) | NR1H4 | |
| SCHEMBL16377782 | 0.87 | CCNA2 (0.33) | CCNA2CDK2CCNA1TGFBR1ACVR1 | |
| SCHEMBL16334004 | 0.86 | CNR2 (0.33) | CCNA2CDK2CCNA1MAPTPOLB | |
| SCHEMBL16377828 | 0.85 | CCNA2 (0.32) | CCNA2CDK2CCNA1TGFBR1ACVR1 | |
| SCHEMBL16377818 | 0.85 | CCNA2 (0.33) | CCNA2CDK2CCNA1MAPTPOLB | |
| SCHEMBL22626644 | 0.84 | CCNA2 (0.30) | CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |