SCHEMBL16378657

SCHEMBL16378657

O=C(O)CCC(NC(=O)NC(CCCCNC(=O)CCCCCO)C(=O)O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 18/20 0.65
RIMKLA Q8IXN7 1/20 0.55
NAALAD2 Q9Y3Q0 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16518793 0.91 FOLH1 (0.70) FOLH1RIMKLANAALAD2
SCHEMBL20698817 0.90 FOLH1 (0.65) FOLH1RIMKLANAALAD2
SCHEMBL20879610 0.88 FOLH1 (0.74) FOLH1RIMKLANAALAD2
SCHEMBL15003787 0.88 FOLH1 (0.67) FOLH1RIMKLANAALAD2
SCHEMBL19389448 0.88 FOLH1 (0.74) FOLH1RIMKLANAALAD2
SCHEMBL23252356 0.88 FOLH1 (0.67) FOLH1RIMKLANAALAD2
SCHEMBL22130972 0.88 FOLH1 (0.74) FOLH1RIMKLANAALAD2
SCHEMBL22237179 0.88 FOLH1 (0.67) FOLH1RIMKLANAALAD2
SCHEMBL18030076 0.88 FOLH1 (0.67) FOLH1RIMKLANAALAD2
SCHEMBL21417883 0.88 FOLH1 (0.67) FOLH1RIMKLANAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014210485-A1 DOCETAXEL POLYMERIC NANOPARTICLES FOR CANCER TREATMENT BIND THERAPEUTICS, INC. (US) 2014-12-31 WO disclosed