SCHEMBL16379490

SCHEMBL16379490

C=CC(=O)OCCCCCOc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OC)cc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
NPC1 O15118 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
HTT P42858 3/20 0.48
CYP3A4 P08684 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP2D6 P10635 1/20 0.48
THRB P10828 1/20 0.48
TSHR P16473 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 5/20 0.47
KMT2A Q03164 3/20 0.47
GFER P55789 1/20 0.47
GAA P10253 1/20 0.46
PRSS1 P07477 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13927211 1.00 LMNA (0.50) LMNANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL16379456 1.00 LMNA (0.50) LMNANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL13903655 1.00 LMNA (0.50) LMNANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL10013680 1.00 LMNA (0.50) LMNANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL1958900 1.00 LMNA (0.50) LMNANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL13997907 1.00 LMNA (0.50) LMNANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL24599286 1.00 LMNA (0.50) LMNANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL6517575 1.00 LMNA (0.50) LMNANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL14275368 0.99 LMNA (0.49) LMNANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL12172636 0.99 LMNA (0.49) LMNANPC1SMN1; SMN2NFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-07-09 US disclosed
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-07-09 US disclosed
US-20150002789-A1 OPTICALLY-COMPENSATORY FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD OF PRODUCING OPTICALLY-COMPENSATORY FILM FUJIFILM CORPORATION (JP) 2015-01-01 US disclosed
US-20150002789-A1 OPTICALLY-COMPENSATORY FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD OF PRODUCING OPTICALLY-COMPENSATORY FILM FUJIFILM CORPORATION (JP) 2015-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM PYM1, C9, LANCL2 LMNA 210/4885NPC1 626/4885SMN1; SMN2 2516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.