Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2822604 | 0.85 | FFAR1 (0.56) | HDAC1HDAC7FFAR1FFAR4 | |
| SCHEMBL5381994 | 0.83 | KMT2A (0.44) | HRH3HDAC1HDAC7FFAR1FFAR4 | |
| SCHEMBL5381126 | 0.80 | PTGDR2 (0.48) | HRH3HDAC1HDAC7FFAR1FFAR4 | |
| SCHEMBL7549149 | 0.79 | GPR34 (0.43) | HRH3HDAC1HDAC7KMT2AMEN1 | |
| SCHEMBL5380946 | 0.78 | CYP19A1 (0.44) | KMT2AMEN1ALDH1A1CYP19A1 | |
| SCHEMBL5372077 | 0.75 | CYP19A1 (0.48) | HRH3HDAC1HDAC7KMT2AMEN1 | |
| SCHEMBL5377099 | 0.75 | FFAR1 (0.56) | HDAC1HDAC7FFAR1FFAR4ALDH1A1 | |
| SCHEMBL7564649 | 0.75 | MAOB (0.45) | HRH3HDAC1FFAR4KMT2AMEN1 | |
| SCHEMBL5372015 | 0.74 | KMT2A (0.65) | KMT2AMEN1ALDH1A1CYP19A1PTGS2 | |
| SCHEMBL5384888 | 0.74 | HDAC1 (0.55) | HRH3HDAC1HDAC7FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1731505-B1 | ALKOXYPHENYLPROPANOIC ACID DERIVATIVES | TAKEDA PHARMACEUTICAL (JP) | 2015-01-14 | — | — | EP | disclosed |