Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDA | P32320 | 8/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20427403 | 1.00 | CDA (0.39) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL18798692 | 0.89 | CDA (0.33) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL19229350 | 0.88 | CDA (0.39) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL26311383 | 0.88 | CDA (0.48) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL17232101 | 0.87 | CYP3A4 (0.30) | — | |
| SCHEMBL15187536 | 0.86 | ADORA2A (0.38) | CDA | |
| SCHEMBL14583693 | 0.86 | ADORA2A (0.38) | CDA | |
| SCHEMBL18875014 | 0.86 | ADORA2A (0.38) | CDA | |
| SCHEMBL18593480 | 0.85 | CDA (0.34) | CDAPDE4DPDE3ASLC29A1 | |
| SCHEMBL15702140 | 0.85 | CDA (0.34) | CDAPDE4DPDE3ASLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016189040-A1 | SELECTIVE PROCESS FOR SYNTHESIS OF NUCLEOSIDE PHOSPHORAMIDATES | SANDOZ AG (CH) | 2016-12-01 | — | — | WO | disclosed |
| EP-2826784-A1 | Nucleoside phosphoramidate prodrugs | Gilead Pharmasset LLC (US) | 2015-01-21 | — | — | EP | disclosed |
| EP-2824109-A1 | Nucleoside phosphoramidate prodrugs | Gilead Pharmasset LLC (US) | 2015-01-14 | — | — | EP | disclosed |