SCHEMBL26311383

SCHEMBL26311383

C=C1NC(=O)C=CN1C1OC(CO)C(O)C1(F)F

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CDA P32320 8/20 0.48
▸ PDE4D Q08499 1/20 0.44
▸ PDE3A Q14432 1/20 0.44
▸ SLC29A1 Q99808 1/20 0.44
▸ LMNA P02545 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20427403 0.88 CDA (0.39) CDAPDE4DPDE3ASLC29A1
SCHEMBL16381996 0.88 CDA (0.39) CDAPDE4DPDE3ASLC29A1
SCHEMBL19229350 0.88 CDA (0.39) CDAPDE4DPDE3ASLC29A1
SCHEMBL15187536 0.84 ADORA2A (0.38) CDA
SCHEMBL14583693 0.84 ADORA2A (0.38) CDA
SCHEMBL18875014 0.84 ADORA2A (0.38) CDA
SCHEMBL18593480 0.82 CDA (0.34) CDAPDE4DPDE3ASLC29A1
SCHEMBL15702140 0.82 CDA (0.34) CDAPDE4DPDE3ASLC29A1
SCHEMBL18798692 0.81 CDA (0.33) CDAPDE4DPDE3ASLC29A1
SCHEMBL16125739 0.79 CDA (0.31) CDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230277576-A1 A METHOD FOR PREVENTING OR TREATING A CORNAVIRUS INFECTIOUS DISEASE HENAN GENUINE BIOTECH CO., LTD. (CN) 2023-09-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230277576-A1 A METHOD FOR PREVENTING OR TREATING A CORNAVIRUS INFECTIOUS DISEASE ACE, ACE2, SARS1 CDA 1502/4885PDE4D 3478/4885PDE3A 1487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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