Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9963980 | 1.00 | HSD11B1 (0.84) | HSD11B1 | |
| SCHEMBL15139375 | 1.00 | HSD11B1 (0.84) | HSD11B1 | |
| SCHEMBL15139374 | 1.00 | HSD11B1 (0.84) | HSD11B1 | |
| SCHEMBL9963982 | 1.00 | HSD11B1 (0.84) | HSD11B1 | |
| SCHEMBL9963978 | 1.00 | HSD11B1 (0.84) | HSD11B1 | |
| SCHEMBL15139464 | 0.91 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL9964122 | 0.91 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL1949231 | 0.91 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL1949234 | 0.91 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL1953008 | 0.90 | HSD11B1 (1.00) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635563-B1 | CRYSTALLINE FORMS OF HYDROCHLORIDE SALT OF (4A-R,9A-S)-1-(1H-BENZOIMIDAZOLE-5-CARBONYL)-2,3,4,4A,9,9A-HEXAHYDRO-1H-INDENO [2,1-B]PYRIDINE-6-CARBONITRILE AND THEIR USE AS HSD 1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2015-01-14 | — | — | EP | disclosed |