Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 12/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16381561 | 0.96 | MEN1 (0.48) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL8984777 | 0.96 | MEN1 (0.48) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL17443129 | 0.96 | MEN1 (0.48) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL17789210 | 0.89 | ESR1 (0.51) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL19307998 | 0.87 | ESR1 (0.53) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL8984804 | 0.85 | MAPT (0.55) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL18327684 | 0.85 | ESR1 (0.50) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL4271007 | 0.85 | ESR1 (0.50) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL20942083 | 0.85 | ESR1 (0.50) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL28227922 | 0.79 | PDK2 (0.39) | MEN1KMT2AKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3016956-B1 | DIANHYDRIDES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE | UNIV KING ABDULLAH SCI & TECH (SA) | 2019-02-20 | — | — | EP | disclosed |
| US-9840514-B2 | Dianhydrides, polyimides, methods of making each, and methods of use | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2017-12-12 | — | — | US | disclosed |
| US-20160152630-A1 | DIANHYDRIDES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2016-06-02 | — | — | US | disclosed |
| WO-2015001422-A2 | DIANHYDRIDES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2015-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152630-A1 | DIANHYDRIDES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE | ALKBH3, ALK, DDC | MEN1 1957/4885KMT2A 595/4885KDM4E 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.