Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755662 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL28287301 | 0.91 | MEN1 (0.61) | MEN1KMT2AMTNR1AMTNR1BRECQL | |
| SCHEMBL26018096 | 0.85 | MEN1 (0.45) | MEN1KMT2AMTNR1AMTNR1BRECQL | |
| SCHEMBL14258481 | 0.84 | MEN1 (0.54) | MEN1KMT2AMTNR1AMTNR1BRECQL | |
| SCHEMBL15482299 | 0.84 | MEN1 (0.54) | MEN1KMT2AMTNR1AMTNR1BRECQL | |
| SCHEMBL9921438 | 0.84 | MEN1 (0.58) | MEN1KMT2ARECQLCYP2C9NAAA | |
| SCHEMBL9921406 | 0.84 | MEN1 (0.58) | MEN1KMT2ARECQLCYP2C9NAAA | |
| SCHEMBL9921400 | 0.84 | MEN1 (0.58) | MEN1KMT2ARECQLCYP2C9NAAA | |
| SCHEMBL9921399 | 0.84 | MEN1 (0.58) | MEN1KMT2ARECQLCYP2C9NAAA | |
| SCHEMBL9921398 | 0.84 | MEN1 (0.58) | MEN1KMT2ARECQLCYP2C9NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150005319-A1 | MACROCYCLIC COMPOUNDS FOR MODULATING IL-17 | ENSEMBLE THERAPEUTICS CORPORATION | 2015-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005319-A1 | MACROCYCLIC COMPOUNDS FOR MODULATING IL-17 | IL17A, IL15, IL2 | MEN1 1132/4885KMT2A 3399/4885MTNR1A 1954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.