SCHEMBL1638488

SCHEMBL1638488

NCCOS(=O)(=O)CCN

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
SLC6A6 P31641 1/20 0.39
CYP2C19 P33261 1/20 0.39
BLM P54132 1/20 0.39
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
CA1 P00915 7/20 0.32
CA2 P00918 7/20 0.32
CA9 Q16790 7/20 0.32
CA12 O43570 2/20 0.31
CA3 P07451 2/20 0.31
CA4 P22748 2/20 0.31
CA6 P23280 2/20 0.31
CA5A P35218 2/20 0.31
CA7 P43166 2/20 0.31
CA14 Q9ULX7 2/20 0.31
CA5B Q9Y2D0 2/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29449503 0.97 LMNA (0.38) LMNASLC6A6CYP2C19BLMALDH1A1
SCHEMBL27517031 0.97 LMNA (0.38) LMNASLC6A6CYP2C19BLMALDH1A1
SCHEMBL28593624 0.84 APP (0.44) LMNASLC6A6CYP2C19BLMALDH1A1
SCHEMBL10631910 0.82 CA1 (0.44) LMNAALDH1A1CA1CA2CA9
SCHEMBL5328947 0.82 LMNA (0.40) LMNASLC6A6CYP2C19BLMALDH1A1
SCHEMBL7098756 0.82 LMNA (0.35) LMNASLC6A6CYP2C19BLMALDH1A1
SCHEMBL9118375 0.82 CA1 (0.52) LMNASLC6A6CYP2C19BLMALDH1A1
SCHEMBL28507033 0.80 LMNA (0.39) LMNASLC6A6CYP2C19BLMALDH1A1
SCHEMBL8859260 0.79 CA1 (0.56) LMNABLMALDH1A1HPGDCA1
Ethylene SCHEMBL28013346 0.79 CA1 (0.48) LMNASLC6A6CYP2C19BLMCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12269247-B2 Process for recycling of bonded articles BASF SE (DE) 2025-04-08 US disclosed
WO-2024083787-A1 STORAGE-STABLE COATED PARTICLES AND THEIR PREPARATION BASF SE (DE) 2024-04-25 WO disclosed
US-20230211598-A1 PROCESS FOR RECYCLING OF BONDED ARTICLES BASF SE (DE) 2023-07-06 US disclosed
EP-4161768-A1 PROCESS FOR RECYCLING OF BONDED ARTICLES BASF SE (DE) 2023-04-12 EP disclosed
CN-114634677-A Aqueous dispersion composition and preparation method and application thereof 万华化学集团股份有限公司 2022-06-17 CN disclosed
WO-2021249749-A1 PROCESS FOR RECYCLING OF BONDED ARTICLES BASF SE (DE) 2021-12-16 WO disclosed
EP-3475344-A1 DISTILLATIVE SEPARATION OF KETAZINE FROM POLYURETHANE DISPERSIONS Covestro Deutschland AG (DE) 2019-05-01 EP disclosed
EP-3397668-A1 AQUEOUS POLYURETHANE-UREA DISPERSION Covestro Deutschland AG (DE) 2018-11-07 EP disclosed
WO-2017166282-A1 GLOVE DIC CORPORATION (JP) 2017-10-05 WO disclosed
CN-106999842-A CO2 capture process using Vibrio ammoniathermus carbonic anhydrase 二氧化碳处理公司 2017-08-01 CN disclosed
US-20050153865-A1 Cationically modified, anionic polyurethane dispersions BASF AKTIENGESELLSCHAFT (DE) 2005-07-14 US disclosed
US-20040220179-A1 Substituted 1,4-diazepines and uses thereof ORTHO-MCNEIL PHARMACEUTICAL, INC. 2004-11-04 US disclosed
US-6762241-B1 SOLUTION POLYMERIZATION INCLUDING MONOAMINO FUNCTIONAL TRIALKOXYSILANE CHAIN STOPPER; HIGH MOLECULAR WEIGHT; ODORLESS COATINGS; ADHESION; HYDROLYSIS STABILITY; MOISTURE PERMEABLE; WATERFASTNESS BAYER AKTIENGESELLSCHAFT (DE) 2004-07-13 US disclosed
US-6562894-B1 Aqueous reactive putties (II) BAYER AKTIENGESELLSCHAFT (DE) 2003-05-13 US disclosed
CN-1089455-C Charging member and image forming apparatus using the same CANON KK (JP) 2002-08-21 CN disclosed
CN-1345345-A Polyurethane solutions containing alkoxysilane structural units BAYER AG (DE) 2002-04-17 CN disclosed
CN-1345344-A Self-crosslinking polyurethane, polyurethane-polyurea or polyurea dispersions for sizing agents BAYER AG (DE) 2002-04-17 CN disclosed
CN-1118891-A Charging member and image forming apparatus using the same CANON KK (JP) 1996-03-20 CN disclosed
US-4810628-A ANIONIC POLYURETHANE BINDER AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1989-03-07 US disclosed
US-4728542-A POLYURETHANES; WATER VAPOR PERMEABLE COATINGS BAYER AKTIENGESELLSCHAFT (DE) 1988-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040220179-A1 Substituted 1,4-diazepines and uses thereof TP53, MDM2, HRH2 LMNA 3185/4885SLC6A6 4732/4885CYP2C19 2901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.