Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21422716 | 0.93 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNACTSLCTSSMME | |
| SCHEMBL16384723 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNACTSLCTSSMME | |
| SCHEMBL21422694 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNACTSLCTSSMME | |
| SCHEMBL16384896 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNACTSLCTSSMME | |
| SCHEMBL30634608 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNACTSLCTSSSIRT2 | |
| SCHEMBL10739937 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2CTSLCTSSMMEECE1 | |
| SCHEMBL10746514 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2CTSLCTSSMMEECE1 | |
| SCHEMBL30914622 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2CTSLCTSSMMEECE1 | |
| SCHEMBL29437121 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2CTSLCTSSMMEECE1 | |
| SCHEMBL12109818 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2CTSLCTSSMMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015006728-A2 | SITE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS | USERA AIMEE (US) | 2015-01-15 | — | — | WO | disclosed |