Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16385192 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNACAPN1CAPN2SIRT2 | |
| SCHEMBL15382100 | 0.83 | LMNA (0.57) | SMN1; SMN2LMNACAPN1CAPN2SIRT2 | |
| SCHEMBL14240585 | 0.83 | SIRT2 (0.58) | CAPN1CAPN2SIRT2TPSAB1SIRT1 | |
| SCHEMBL25132909 | 0.83 | SIRT2 (0.57) | SMN1; SMN2CAPN1CAPN2SIRT2CTSL | |
| SCHEMBL25132765 | 0.82 | SYK (0.49) | SMN1; SMN2LMNACAPN1CAPN2SIRT2 | |
| SCHEMBL25273830 | 0.81 | SIRT2 (0.59) | SMN1; SMN2LMNACAPN1CAPN2SIRT2 | |
| SCHEMBL25260928 | 0.81 | FOLH1 (0.59) | SMN1; SMN2LMNASIRT2 | |
| SCHEMBL25273831 | 0.81 | SIRT2 (0.59) | SMN1; SMN2LMNACAPN1CAPN2SIRT2 | |
| SCHEMBL29336444 | 0.80 | LMNA (0.54) | SMN1; SMN2LMNACAPN1CAPN2SIRT2 | |
| SCHEMBL29467642 | 0.80 | LMNA (0.54) | SMN1; SMN2LMNACAPN1CAPN2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250289842-A1 | Processes for Making NAG-25, a Carbohydrate Targeting Moiety, and its Intermediates | AMGEN INC. | 2025-09-18 | — | — | US | disclosed |
| EP-4519278-A1 | PROCESSES FOR MAKING NAG-25, A CARBOHYDRATE TARGETING MOIETY, AND ITS INTERMEDIATES | Amgen Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215306-A1 | PROCESSES FOR MAKING NAG-25, A CARBOHYDRATE TARGETING MOIETY, AND ITS INTERMEDIATES | AMGEN INC. (US) | 2023-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250289842-A1 | Processes for Making NAG-25, a Carbohydrate Targeting Moiety, and its Intermediates | ENGASE, MAN2B2, GALNT2 | SMN1; SMN2 2575/4885LMNA 3248/4885CAPN1 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.