Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 19/20 | 0.87 |
| ▸ | PTAFR | P25105 | 1/20 | 0.87 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.68 |
| ▸ | FNTA | P49354 | 1/20 | 0.65 |
| ▸ | FNTB | P49356 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rupatadine SCHEMBL30730975 | 0.93 | HRH1 (1.00) | HRH1PTAFRKCNH2FNTAFNTB | |
| Rupatadine SCHEMBL29400290 | 0.93 | HRH1 (1.00) | HRH1PTAFRKCNH2FNTAFNTB | |
| Rupatadine SCHEMBL27703 | 0.93 | HRH1 (1.00) | HRH1PTAFRKCNH2FNTAFNTB | |
| SCHEMBL9138981 | 0.93 | HRH1 (0.80) | HRH1PTAFRKCNH2FNTAFNTB | |
| SCHEMBL9142787 | 0.93 | HRH1 (1.00) | HRH1PTAFRKCNH2FNTAFNTB | |
| Rupatadine SCHEMBL28585002 | 0.93 | HRH1 (0.98) | HRH1PTAFRKCNH2FNTAFNTB | |
| Rupatadine SCHEMBL1649670 | 0.93 | HRH1 (0.98) | HRH1PTAFRKCNH2FNTAFNTB | |
| SCHEMBL9136454 | 0.92 | HRH1 (1.00) | HRH1PTAFRKCNH2FNTAFNTB | |
| SCHEMBL9140352 | 0.89 | HRH1 (0.85) | HRH1PTAFRKCNH2 | |
| Rupatadine SCHEMBL28086201 | 0.89 | HRH1 (0.90) | HRH1PTAFRKCNH2FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2824103-B1 | An improved process for the preparation of Rupatadine Fumarate | CADILA PHARMACEUTICALS LTD (IN) | 2016-04-27 | — | — | EP | disclosed |
| EP-2824103-A1 | An improved process for the preparation of Rupatadine Fumarate | Cadila Pharmaceuticals Limited (IN) | 2015-01-14 | — | — | EP | disclosed |