Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | MERTK | Q12866 | 2/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409766 | 0.87 | VCAM1 (0.66) | VCAM1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8409874 | 0.82 | VCAM1 (0.59) | VCAM1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7886443 | 0.81 | VCAM1 (0.58) | VCAM1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL8412969 | 0.81 | VCAM1 (0.58) | VCAM1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL645653 | 0.80 | VCAM1 (1.00) | VCAM1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL25186726 | 0.79 | VCAM1 (0.56) | VCAM1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1509524 | 0.79 | VCAM1 (0.56) | VCAM1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL15413658 | 0.79 | VCAM1 (0.77) | VCAM1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6463 | 0.79 | VCAM1 (1.00) | VCAM1MERTKKAT2BMAPTMAPK1 | |
| SCHEMBL12253372 | 0.79 | VCAM1 (1.00) | VCAM1MERTKKAT2BMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376376-B2 | Substitute diphenylamine compounds use thereof as antitumor agents | SINOCHEM CORPORATION (CN) | 2016-06-28 | — | — | US | disclosed |
| US-20150011628-A1 | SUBSTITUTE DIPHENYLAMINE COMPOUNDS USE THEREOF AS ANTITUMOR AGENTS | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011628-A1 | SUBSTITUTE DIPHENYLAMINE COMPOUNDS USE THEREOF AS ANTITUMOR AGENTS | MCL1, BRCA1, FLI1 | VCAM1 4495/4885ALDH1A1 91/4885GRIN2D 4425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.