SCHEMBL163879

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL166876	0.94	CXCR3 (0.59)	CXCR3KCNH2GRIN2BGRIN1MAPT
	SCHEMBL3732635	0.94	CXCR3 (0.59)	CXCR3KCNH2GRIN2BGRIN1MAPT
	SCHEMBL167757	0.93	CXCR3 (0.73)	CXCR3KCNH2GRIN2BGRIN1MAPT
	SCHEMBL164210	0.89	CXCR3 (0.60)	CXCR3KCNH2GRIN2BGRIN1MAPT
	SCHEMBL168189	0.89	CXCR3 (0.54)	CXCR3KCNH2GRIN2BGRIN1MAPT
	SCHEMBL3726632	0.88	CXCR3 (0.52)	CXCR3KCNH2GRIN2BGRIN1MAPT
	SCHEMBL168188	0.87	CXCR3 (0.51)	CXCR3KCNH2GRIN2BGRIN1MAPT
	SCHEMBL3726229	0.84	CXCR3 (0.60)	CXCR3KCNH2GRIN2BGRIN1MAPT
	SCHEMBL113350	0.79	CXCR3 (0.51)	CXCR3KCNH2GRIN2BGRIN1
	SCHEMBL113349	0.79	CXCR3 (0.50)	CXCR3KCNH2GRIN2BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.