Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL657320 | 0.92 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1MAPTALDH1A1CXCR1 | |
| SCHEMBL655367 | 0.90 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1MAPTALDH1A1LMNA | |
| SCHEMBL3715889 | 0.89 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1MAPTALDH1A1CXCR1 | |
| SCHEMBL3715890 | 0.89 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1MAPTALDH1A1CXCR1 | |
| SCHEMBL656133 | 0.85 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1MAPTALDH1A1CXCR1 | |
| SCHEMBL656132 | 0.85 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1MAPTALDH1A1CXCR1 | |
| SCHEMBL7885798 | 0.84 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL16388413 | 0.84 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1MAPT | |
| SCHEMBL656515 | 0.81 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1MAPT | |
| SCHEMBL658893 | 0.81 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421833-B1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2015-01-14 | — | — | EP | disclosed |