Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.75 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912585 | 1.00 | MMP13 (0.75) | MMP13MMP2 | |
| SCHEMBL16389081 | 0.92 | MMP13 (0.74) | MMP13MMP2 | |
| SCHEMBL1316545 | 0.92 | MMP13 (0.74) | MMP13MMP2 | |
| SCHEMBL12120765 | 0.89 | MMP13 (0.70) | MMP13MMP2 | |
| SCHEMBL1318706 | 0.87 | MMP13 (0.80) | MMP13MMP2 | |
| SCHEMBL1315900 | 0.86 | MMP13 (0.79) | MMP13MMP2 | |
| SCHEMBL1319146 | 0.86 | MMP13 (1.00) | MMP13MMP2 | |
| SCHEMBL12123421 | 0.86 | MMP13 (0.79) | MMP13MMP2 | |
| SCHEMBL1315796 | 0.85 | MMP13 (0.81) | MMP13MMP2 | |
| SCHEMBL1317274 | 0.84 | MMP13 (0.73) | MMP13MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346831-B1 | HETEROARYL DIAMIDE COMPOUNDS USEFUL AS MMP-13 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2015-01-07 | — | — | EP | disclosed |