Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16389115 | 0.92 | MMP13 (0.54) | MMP13 | |
| SCHEMBL1317587 | 0.89 | MMP13 (0.79) | MMP13 | |
| SCHEMBL16389112 | 0.84 | MMP13 (0.53) | MMP13 | |
| SCHEMBL1317415 | 0.81 | MMP13 (0.68) | MMP13 | |
| SCHEMBL1316524 | 0.79 | MMP13 (0.80) | MMP13 | |
| SCHEMBL1319025 | 0.79 | MMP13 (0.80) | MMP13 | |
| SCHEMBL1317773 | 0.77 | MMP13 (1.00) | MMP13 | |
| SCHEMBL7905319 | 0.77 | MMP13 (1.00) | MMP13 | |
| SCHEMBL16389108 | 0.77 | MMP13 (0.67) | MMP13 | |
| SCHEMBL1315788 | 0.76 | MMP13 (0.63) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346831-B1 | HETEROARYL DIAMIDE COMPOUNDS USEFUL AS MMP-13 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2015-01-07 | — | — | EP | disclosed |