Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 19/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911631 | 1.00 | MMP13 (1.00) | MMP13NPC1RAB9AL3MBTL1 | |
| SCHEMBL7913065 | 0.99 | MMP13 (0.98) | MMP13NPC1RAB9AL3MBTL1 | |
| SCHEMBL7909649 | 0.94 | MMP13 (0.89) | MMP13NPC1RAB9AL3MBTL1 | |
| SCHEMBL1320127 | 0.90 | MMP13 (1.00) | MMP13 | |
| SCHEMBL7912458 | 0.89 | MMP13 (0.81) | MMP13NPC1RAB9AL3MBTL1 | |
| SCHEMBL16389137 | 0.89 | MMP13 (0.81) | MMP13NPC1RAB9AL3MBTL1 | |
| SCHEMBL7912168 | 0.89 | MMP13 (0.82) | MMP13 | |
| SCHEMBL1316651 | 0.89 | MMP13 (0.82) | MMP13 | |
| SCHEMBL7912546 | 0.89 | MMP13 (0.82) | MMP13 | |
| SCHEMBL16389136 | 0.89 | MMP13 (0.82) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346831-B1 | HETEROARYL DIAMIDE COMPOUNDS USEFUL AS MMP-13 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2015-01-07 | — | — | EP | disclosed |