⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12894429 | 1.00 | — | — | |
| SCHEMBL1911322 | 1.00 | — | — | |
| SCHEMBL15384870 | 0.94 | PIK3CD (0.31) | — | |
| SCHEMBL20842925 | 0.80 | HSD17B10 (0.30) | — | |
| SCHEMBL473650 | 0.79 | — | — | |
| SCHEMBL28790509 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL3313521 | 0.77 | PIK3CD (0.36) | — | |
| SCHEMBL10605599 | 0.77 | — | — | |
| SCHEMBL2855554 | 0.77 | — | — | |
| SCHEMBL27515856 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271960-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS INC (US) | 2023-08-31 | — | — | US | disclosed |
| US-20230181546-A1 | TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS | PLIANT THERAPEUTICS INC (US) | 2023-06-15 | — | — | US | disclosed |
| US-20180133349-A1 | Radiolabeled GRPR-Antagonists For Diagnostic Imaging and Treatment of GRPR-Positive Cancer | ADVANCED ACCELERATOR APPLICATIONS INTERNATIONAL SA (CH) | 2018-05-17 | — | — | US | disclosed |
| US-9839703-B2 | Radiolabeled GRPR-antagonists for diagnostic imaging and treatment of GRPR-positive cancer | ADVANCED ACCELERATOR APPLICATIONS USA, INC. (US) | 2017-12-12 | — | — | US | disclosed |
| US-20170312203-A1 | SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER | JOHNSON & JOHNSON CONSUMER INC. (US) | 2017-11-02 | — | — | US | disclosed |
| US-9776972-B2 | Pyrazole derivatives as arginine methyltransferase inhibitors and uses thereof | EPIZYME INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-9737471-B2 | Sunscreen compositions containing an ultraviolet radiation-absorbing polymer | JOHNSON & JOHNSON CONSUMER INC. (US) | 2017-08-22 | — | — | US | disclosed |
| US-20170217913-A1 | A NEW CLASS OF MU-OPIOID RECEPTOR AGONISTS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-08-03 | — | — | US | disclosed |
| US-20160137609-A1 | PYRAZOLE DERIVATIVES AS ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-05-19 | — | — | US | disclosed |
| US-9254254-B2 | Sunscreen compositions containing an ultraviolet radiation-absorbing polymer | JOHNSON & JOHNSON CONSUMER INC. (US) | 2016-02-09 | — | — | US | disclosed |
| US-9248092-B2 | Sunscreen compositions containing an ultraviolet radiation-absorbing polymer | JOHNSON & JOHNSON CONSUMER INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150265732-A1 | GRPR-ANTAGONISTS FOR DETECTION, DIAGNOSIS AND TREATMENT OF GRPR-POSITIVE CANCER | ADVANCED ACCELERATOR APPLICATIONS INTERNATIONAL SA (CH) | 2015-09-24 | — | — | US | disclosed |
| US-20150164771-A1 | SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER | JOHNSON & JOHNSON CONSUMER INC. | 2015-06-18 | — | — | US | disclosed |
| US-20150104401-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | JOHNSON & JOHNSON CONSUMER INC. | 2015-04-16 | — | — | US | disclosed |
| US-8986665-B2 | Cationic polyglyceryl compositions and compounds | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2015-03-24 | — | — | US | disclosed |
| US-8961945-B2 | Cationic polyglyceryl compositions and compounds | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| WO-2014178954-A1 | PYRAZOLE DERIVATIVES AS ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-11-06 | — | — | WO | disclosed |
| US-20140044661-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUND | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2014-02-13 | — | — | US | disclosed |
| US-20120093753-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | JOHNSON & JOHNSON CONSUMER INC. | 2012-04-19 | — | — | US | disclosed |
| US-20120087882-A1 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUNDS | KENVUE BRANDS LLC | 2012-04-12 | — | — | US | disclosed |