Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21022481 | 1.00 | LMNA (0.45) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL18828509 | 1.00 | LMNA (0.45) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL16392636 | 1.00 | LMNA (0.45) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL32681156 | 1.00 | LMNA (0.45) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL16392631 | 1.00 | LMNA (0.45) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL12969188 | 1.00 | LMNA (0.45) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL16392624 | 1.00 | LMNA (0.45) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL3658171 | 1.00 | LMNA (0.45) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL25976530 | 0.89 | LMNA (0.41) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL21388429 | 0.89 | LMNA (0.38) | LMNAPOLBALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017174657-A1 | NUCLEIC ACID LINKED TO A TRIVALENT GLYCOCONJUGATE | SILENCE THERAPEUTICS GMBH (DE) | 2017-10-12 | — | — | WO | disclosed |
| US-9345781-B2 | Targeted dendrimer-drug conjugates | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-05-24 | — | — | US | disclosed |
| WO-2015006740-A2 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-01-15 | — | — | WO | disclosed |