⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113475 | 0.80 | — | — | |
| SCHEMBL106244 | 0.80 | — | — | |
| SCHEMBL16776729 | 0.80 | CD44 (0.72) | — | |
| Bromide SCHEMBL10391086 | 0.77 | CD44 (0.68) | — | |
| Bromide SCHEMBL29216576 | 0.77 | CES2 (0.39) | — | |
| Ammonia Solution, Strong SCHEMBL1289383 | 0.77 | CD44 (0.68) | — | |
| Lithium SCHEMBL30421931 | 0.77 | CD44 (0.68) | — | |
| Hydrochloric Acid SCHEMBL7423355 | 0.77 | CES2 (0.39) | — | |
| Methane SCHEMBL1703075 | 0.77 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL6687694 | 0.77 | CD44 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 523 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707773-A | Preparation method and application of maleimide structure-containing compound | 中国农业大学 | 2025-03-28 | — | — | CN | claimed |
| CN-119528816-A | PARP-1 inhibitor and preparation method thereof | 吉林省药物研究院 | 2025-02-28 | — | — | CN | claimed |
| CN-115650851-A | Preparation method of 2-fluoro-4-bromo-6-methyl benzoate | 无锡双启科技有限公司 | 2023-01-31 | — | — | CN | claimed |
| US-10472375-B2 | 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivative | PULMOCIDE LIMITED (GB) | 2019-11-12 | — | — | US | claimed |
| US-20190202841-A1 | Novel 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivative | PULMOCIDE LTD (GB) | 2019-07-04 | — | — | US | claimed |
| EP-3204389-B1 | NOVEL 5,6-DIHYDRO-4H-BENZO[B]THIENO-[2,3-D]AZEPINE DERIVATIVE | PULMOCIDE LTD (GB) | 2019-06-26 | — | — | EP | claimed |
| US-10035810-B2 | 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivative | PULMOCIDE LIMITED (GB) | 2018-07-31 | — | — | US | claimed |
| US-20180179228-A1 | NOVEL 5,6-DIHYDRO-4H-BENZO[B]THIENO-[2,3-D]AZEPINE DERIVATIVE | PULMOCIDE LIMITED (GB) | 2018-06-28 | — | — | US | claimed |
| EP-3204389-A1 | NOVEL 5,6-DIHYDRO-4H-BENZO[B]THIENO-[2,3-D]AZEPINE DERIVATIVE | Pulmocide Limited (GB) | 2017-08-16 | — | — | EP | claimed |
| EP-2906559-B1 | AZAINDOLINES | HOFFMANN LA ROCHE (CH) | 2017-02-08 | — | — | EP | claimed |
| WO-2016055791-A1 | Novel 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivative | PULMOCIDE LIMITED (GB) | 2016-04-14 | — | — | WO | claimed |
| US-9309248-B2 | Azaindolines | HOFFMANN-LA ROCHE INC. (US) | 2016-04-12 | — | — | US | claimed |
| US-20150266879-A1 | AZAINDOLINES | HOFFMANN-LA ROCHE INC. | 2015-09-24 | — | — | US | claimed |
| EP-2906559-A1 | AZAINDOLINES | F. Hoffmann-La Roche AG (CH) | 2015-08-19 | — | — | EP | claimed |
| WO-2014056871-A1 | AZAINDOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-04-17 | — | — | WO | claimed |
| CN-102786460-A | Synthetic method for indole-3-carboxaldehyde compounds | SUZHOU CHUKAI PHARMACEUTICAL CO LTD | 2012-11-21 | — | — | CN | claimed |
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | claimed |
| JP-4330042-A | — | — | None | — | — | JP | disclosed |
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4060635-A | Amidinoureas for treating diarrhea | WILLIAM H. RORER, INC. (US) | 1977-11-29 | — | — | US | disclosed |