Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16398975 | 1.00 | ALDH1A1 (0.33) | ALDH1A1USP2ALOX15TDP1 | |
| SCHEMBL5156225 | 0.89 | ALDH1A1 (0.41) | ALDH1A1USP2ALOX15TDP1 | |
| SCHEMBL16398869 | 0.85 | USP2 (0.31) | ALDH1A1USP2ALOX15TDP1 | |
| SCHEMBL16398866 | 0.85 | USP2 (0.31) | ALDH1A1USP2ALOX15TDP1 | |
| SCHEMBL8199466 | 0.77 | USP2 (0.33) | ALDH1A1USP2ALOX15TDP1 | |
| SCHEMBL27449757 | 0.77 | — | — | |
| SCHEMBL10582891 | 0.76 | ALDH1A1 (0.48) | ALDH1A1USP2ALOX15TDP1 | |
| SCHEMBL21980551 | 0.76 | — | — | |
| SCHEMBL1524549 | 0.74 | — | — | |
| SCHEMBL1525333 | 0.74 | USP2 (0.30) | ALDH1A1USP2ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015008097-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-01-22 | — | — | WO | disclosed |
| WO-2015008097-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-01-22 | — | — | WO | disclosed |